9O9N
Crystal structure of PPARgamma ligand binding domain (LBD) in complex with NCoR1 corepressor peptide and inverse agonist FX-909
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Peroxisome proliferator-activated receptor gamma | polymer | 276 | 31506.6 | 1 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
| 2 | B (D) | Nuclear receptor corepressor 1 | polymer | 23 | 2508.8 | 1 | UniProt (O75376) | Homo sapiens | N-CoR,N-CoR1 |
| 3 | C (B) | (3P)-3-(5,7-difluoro-4-oxo-1,4-dihydroquinolin-2-yl)-4-(methanesulfonyl)benzonitrile | non-polymer | 360.3 | 1 | Chemie (A1CAA) | |||
| 4 | D, E (B, D) | water | water | 18.0 | 41 | Chemie (HOH) |
Sequence modifications
B: 203 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Gly 202 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34015.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 360.3 | |
| All* | Total formula weight | 34375.7 |
