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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

9O3L

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with macrolide erythromycin, mRNA, deacylated A-site tRNAphe, P-site fMRC-peptidyl-tRNAmet, and deacylated E-site tRNAphe at 2.75A resolution

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, FB
(1A, 2A)		23S Ribosomal RNApolymer2915948007.62GenBank (55771382)Thermus thermophilus HB8
2B, GB
(1B, 2B)		5S Ribosomal RNApolymer12139188.42GenBank (AP008226.1)Thermus thermophilus HB8
3C, HB
(1D, 2D)		50S ribosomal protein L2polymer27630532.62UniProt (P60405)
Pfam (PF00181)
Pfam (PF03947)		Thermus thermophilus HB8
4D, IB
(1E, 2E)		50S ribosomal protein L3polymer20622450.22UniProt (Q5SHN8)
Pfam (PF00297)		Thermus thermophilus HB8
5E, JB
(1F, 2F)		50S ribosomal protein L4polymer21023271.92UniProt (Q5SHN9)
Pfam (PF00573)		Thermus thermophilus HB8L1e
6F, KB
(1G, 2G)		50S ribosomal protein L5polymer18221061.62UniProt (Q5SHQ0)
Pfam (PF00281)
Pfam (PF00673)		Thermus thermophilus HB8
7G, LB
(1H, 2H)		50S ribosomal protein L6polymer18019568.92UniProt (P0DOY8)
Pfam (PF00347)		Thermus thermophilus HB8
8H, MB
(1I, 2I)		50S ribosomal protein L9polymer14816422.22UniProt (Q5SLQ1)
Pfam (PF01281)
Pfam (PF03948)		Thermus thermophilus HB8
9I, NB
(1N, 2N)		50S ribosomal protein L13polymer14015927.92UniProt (P60488)
Pfam (PF00572)		Thermus thermophilus HB8
10J, OB
(1O, 2O)		50S ribosomal protein L14polymer12213323.62UniProt (Q5SHP8)
Pfam (PF00238)		Thermus thermophilus HB8
11K, PB
(1P, 2P)		50S ribosomal protein L15polymer15016319.12UniProt (Q5SHQ7)
Pfam (PF00828)		Thermus thermophilus HB8
12L, QB
(1Q, 2Q)		50S ribosomal protein L16polymer14115993.92UniProt (P60489)
Pfam (PF00252)		Thermus thermophilus HB8
13M, RB
(1R, 2R)		50S ribosomal protein L17polymer11813750.12UniProt (Q9Z9H5)
Pfam (PF01196)		Thermus thermophilus HB8
14N, SB
(1S, 2S)		50S ribosomal protein L18polymer11212639.82UniProt (Q5SHQ4)
Pfam (PF00861)		Thermus thermophilus HB8TL24
15O, TB
(1T, 2T)		50S ribosomal protein L19polymer14617188.82UniProt (P60490)
Pfam (PF01245)		Thermus thermophilus HB8
16P, UB
(1U, 2U)		50S ribosomal protein L20polymer11813779.32UniProt (P60491)
Pfam (PF00453)		Thermus thermophilus HB8
17Q, VB
(1V, 2V)		50S ribosomal protein L21polymer10111069.22UniProt (P60492)
Pfam (PF00829)		Thermus thermophilus HB8
18R, WB
(1W, 2W)		50S ribosomal protein L22polymer11312808.12UniProt (Q5SHP3)
Pfam (PF00237)		Thermus thermophilus HB8
19S, XB
(1X, 2X)		50S ribosomal protein L23polymer9610759.82UniProt (Q5SHP0)
Pfam (PF00276)		Thermus thermophilus HB8
20T, YB
(1Y, 2Y)		50S ribosomal protein L24polymer11012085.62UniProt (Q5SHP9)
Pfam (PF00467)
Pfam (PF17136)		Thermus thermophilus HB8
21U, ZB
(1Z, 2Z)		50S ribosomal protein L25polymer20623238.62UniProt (Q5SHZ1)
Pfam (PF01386)
Pfam (PF14693)		Thermus thermophilus HB8TL5
22AC, V
(10, 20)		50S ribosomal protein L27polymer859529.12UniProt (P60493)
Pfam (PF01016)		Thermus thermophilus HB8
23BC, W
(11, 21)		50S ribosomal protein L28polymer9811004.22UniProt (P60494)
Pfam (PF00830)		Thermus thermophilus HB8
24CC, X
(12, 22)		50S ribosomal protein L29polymer728670.32UniProt (Q5SHP6)
Pfam (PF00831)		Thermus thermophilus HB8
25DC, Y
(13, 23)		50S ribosomal protein L30polymer606799.12UniProt (Q5SHQ6)
Pfam (PF00327)		Thermus thermophilus HB8
26EC, Z
(14, 24)		50S ribosomal protein L31polymer718300.52UniProt (Q5SJE1)
Pfam (PF01197)		Thermus thermophilus HB8
27AA, FC
(15, 25)		50S ribosomal protein L32polymer606722.12UniProt (P80339)
Pfam (PF01783)		Thermus thermophilus HB8
28BA, GC
(16, 26)		50S ribosomal protein L33polymer546632.92UniProt (P35871)
Pfam (PF00471)		Thermus thermophilus HB8
29CA, HC
(17, 27)		50S ribosomal protein L34polymer496132.42UniProt (P80340)
Pfam (PF00468)		Thermus thermophilus HB8
30DA, IC
(18, 28)		50S ribosomal protein L35polymer657506.22UniProt (Q5SKU1)
Pfam (PF01632)		Thermus thermophilus HB8
31EA, JC
(19, 29)		50S ribosomal protein L36polymer374435.42UniProt (Q5SHR2)
Pfam (PF00444)		Thermus thermophilus HB8Ribosomal protein B
32FA, KC
(1a, 2a)		16S Ribosomal RNApolymer1521493863.62GenBank (55771382)Thermus thermophilus HB8
33GA, LC
(1b, 2b)		30S ribosomal protein S2polymer25629317.72UniProt (P80371)
Pfam (PF00318)		Thermus thermophilus HB8
34HA, MC
(1c, 2c)		30S ribosomal protein S3polymer23926751.12UniProt (P80372)
Pfam (PF07650)
Pfam (PF00189)		Thermus thermophilus HB8
35IA, NC
(1d, 2d)		30S ribosomal protein S4polymer20924373.42UniProt (P80373)
Pfam (PF00163)
Pfam (PF01479)		Thermus thermophilus HB8
36JA, OC
(1e, 2e)		30S ribosomal protein S5polymer16217583.42UniProt (Q5SHQ5)
Pfam (PF00333)
Pfam (PF03719)		Thermus thermophilus HB8
37KA, PC
(1f, 2f)		30S ribosomal protein S6polymer10111988.82UniProt (Q5SLP8)
Pfam (PF01250)		Thermus thermophilus HB8TS9
38LA, QC
(1g, 2g)		30S ribosomal protein S7polymer15618051.02UniProt (P17291)
Pfam (PF00177)		Thermus thermophilus HB8
39MA, RC
(1h, 2h)		30S ribosomal protein S8polymer13815868.62UniProt (P0DOY9)
Pfam (PF00410)		Thermus thermophilus HB8
40NA, SC
(1i, 2i)		30S ribosomal protein S9polymer12814410.62UniProt (P80374)
Pfam (PF00380)		Thermus thermophilus HB8
41OA, TC
(1j, 2j)		30S ribosomal protein S10polymer10511955.02UniProt (Q5SHN7)
Pfam (PF00338)		Thermus thermophilus HB8
42PA, UC
(1k, 2k)		30S ribosomal protein S11polymer12913737.92UniProt (P80376)
Pfam (PF00411)		Thermus thermophilus HB8
43QA, VC
(1l, 2l)		30S ribosomal protein S12polymer13214683.52UniProt (Q5SHN3)
Pfam (PF00164)		Thermus thermophilus HB8
44RA, WC
(1m, 2m)		30S ribosomal protein S13polymer12614338.92UniProt (P80377)
Pfam (PF00416)		Thermus thermophilus HB8
45SA, XC
(1n, 2n)		30S ribosomal protein S14 type Zpolymer617158.72UniProt (P0DOY6)
Pfam (PF00253)		Thermus thermophilus HB8
46TA, YC
(1o, 2o)		30S ribosomal protein S15polymer8910578.42UniProt (Q5SJ76)
Pfam (PF00312)		Thermus thermophilus HB8
47UA, ZC
(1p, 2p)		30S ribosomal protein S16polymer8810410.02UniProt (Q5SJH3)
Pfam (PF00886)		Thermus thermophilus HB8
48AD, VA
(1q, 2q)		30S ribosomal protein S17polymer10512325.72UniProt (P0DOY7)
Pfam (PF00366)		Thermus thermophilus HB8
49BD, WA
(1r, 2r)		30S ribosomal protein S18polymer8810258.32UniProt (Q5SLQ0)
Pfam (PF01084)		Thermus thermophilus HB8
50CD, XA
(1s, 2s)		30S ribosomal protein S19polymer9310605.52UniProt (Q5SHP2)
Pfam (PF00203)		Thermus thermophilus HB8
51DD, YA
(1t, 2t)		30S ribosomal protein S20polymer10611736.12UniProt (P80380)
Pfam (PF01649)		Thermus thermophilus HB8
52ED, ZA
(1u, 2u)		30S ribosomal protein Thxpolymer273350.02UniProt (Q5SIH3)
Pfam (PF17070)		Thermus thermophilus HB8S31
53AB, FD
(1v, 2v)		MET-PHE-mRNApolymer247804.72Escherichia phage T4
54BB, EB, GD, JD
(1w, 1y, 2w, 2y)		A-site and E-site Deacylated tRNAphepolymer7624644.94GenBank (1850831943)Escherichia coli
55CB, HD
(1x, 2x)		P-site Peptidyl-tRNA fMRC-tRNAcys RNA-partpolymer7724845.92GenBank (1848851804)Escherichia coli
56DB, ID
(1z, 2z)		P-site Peptidyl-tRNA fMRC-tRNAcys Peptide-partpolymer3437.62Escherichia coli
57AAA, AAB, AAC, AAD, ABA...
(1A, 15, 2A, 2a, 1a...)		MAGNESIUM IONnon-polymer24.32713Chemie (MG)
PubChem (888)
58JY, KBC
(1A, 2A)		POTASSIUM IONnon-polymer39.12Chemie (K)
PubChem (813)
59ETA, GRC
(1A, 2A)		ERYTHROMYCIN Anon-polymer733.92Chemie (ERY)
PubChem (16219331)
PubChem (16757675)
PubChem (22489166)
PubChem (22836457)
PubChem (22836628)
PubChem (23229191)
PubChem (24797108)
PubChem (44451949)
PubChem (45107170)
PubChem (45107190)
PubChem (45107269)
PubChem (45107273)
PubChem (49867933)
PubChem (51066560)
PubChem (16219337)
PubChem (16401342)
PubChem (16759276)
PubChem (18397931)
PubChem (18528813)
PubChem (21550772)
PubChem (22836626)
PubChem (44317775)
PubChem (44547821)
PubChem (44563509)
PubChem (45107581)
PubChem (53384904)
PubChem (53384913)
PubChem (50987679)
PubChem (53393685)
PubChem (54359201)
PubChem (57357418)
PubChem (57893297)
PubChem (58594795)
PubChem (58593559)
PubChem (59022390)
PubChem (59062422)
PubChem (59064284)
PubChem (59093569)
PubChem (59284311)
PubChem (59511080)
PubChem (59897430)
PubChem (59903654)
PubChem (60009793)
PubChem (60024420)
PubChem (66639443)
PubChem (66899541)
PubChem (177390461)
PubChem (177679009)
PubChem (3255)
PubChem (8233)
PubChem (9361)
PubChem (57358551)
PubChem (57587180)
PubChem (154401)
PubChem (70897564)
PubChem (71306958)
PubChem (73265320)
PubChem (73456721)
PubChem (73946784)
PubChem (456593)
PubChem (467795)
PubChem (489009)
PubChem (86820632)
PubChem (90473776)
PubChem (90746906)
PubChem (91434318)
PubChem (91558259)
PubChem (97293608)
PubChem (99719271)
PubChem (110189186)
PubChem (6540620)
PubChem (6602506)
PubChem (59974395)
PubChem (60044171)
PubChem (60086513)
PubChem (66577477)
PubChem (6604221)
PubChem (124226124)
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PubChem (124226125)
PubChem (124523502)
PubChem (124604979)
PubChem (124605144)
PubChem (124605146)
PubChem (124716782)
PubChem (124716783)
PubChem (124723147)
PubChem (124762349)
PubChem (124822555)
PubChem (124822558)
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PubChem (163003494)
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PubChem (15986867)
PubChem (16212992)
PubChem (16213052)
PubChem (166604455)
PubChem (166639762)
PubChem (169289157)
PubChem (171114703)
PubChem (172897571)
60AUC, CUC, FAB, IAB, KUC...
(25, 26, 15, 16, 29...)		ZINC IONnon-polymer65.412Chemie (ZN)
61CJB, EDD
(1d, 2d)		IRON/SULFUR CLUSTERnon-polymer351.62Chemie (SF4)
62AFD, AGD, AHD, BFD, BGD...
(1V, 1x, 2j, 1W, 1z...)		waterwater18.03444Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains114
Total formula weight4501686.7
Non-Polymers*Number of molecules2731
Total formula weight68973.7
All*Total formula weight4570660.4
*Water molecules are not included.

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PDB entries from 2026-03-25

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