9O36
CryoEM structure of mu-opioid receptor - Gi protein complex bound to fluornitrazene (FNZ)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 354 | 40415.0 | 1 | UniProt (P63096) | Homo sapiens (human) | Adenylate cyclase-inhibiting G alpha protein |
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 344 | 37671.1 | 1 | UniProt (P62873) | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | C (C) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) | Homo sapiens (human) | G gamma-I |
| 4 | D (E) | scFv16 | polymer | 259 | 27784.9 | 1 | Mus musculus (mouse) | ||
| 5 | E (R) | Mu-type opioid receptor | polymer | 426 | 47910.8 | 1 | UniProt (P42866) | Mus musculus (house mouse) | M-OR-1,MOR-1 |
| 6 | F (R) | N,N-diethyl-2-(2-{[4-(2-fluoroethoxy)phenyl]methyl}-5-nitro-1H-1,3-benzimidazol-1-yl)ethan-1-amine | non-polymer | 414.5 | 1 | Chemie (A1B79) |
Sequence modifications
B: 2 - 340 (UniProt: P62873)
R: 6 - 398 (UniProt: P42866)
| PDB | External Database | Details |
|---|---|---|
| Pro -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gly 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | initiating methionine |
| Lys -18 | - | expression tag |
| Thr -17 | - | expression tag |
| Ile -16 | - | expression tag |
| Ile -15 | - | expression tag |
| Ala -14 | - | expression tag |
| Leu -13 | - | expression tag |
| Ser -12 | - | expression tag |
| Tyr -11 | - | expression tag |
| Ile -10 | - | expression tag |
| Phe -9 | - | expression tag |
| Cys -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Val -6 | - | expression tag |
| Phe -5 | - | expression tag |
| Ala -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Tyr -2 | - | expression tag |
| Lys -1 | - | expression tag |
| Asp 0 | - | expression tag |
| Asp 1 | - | expression tag |
| Asp 2 | - | expression tag |
| Asp 3 | - | expression tag |
| Ala 4 | - | expression tag |
| Met 5 | - | expression tag |
| Asp 399 | - | expression tag |
| Ile 400 | - | expression tag |
| His 401 | - | expression tag |
| His 402 | - | expression tag |
| His 403 | - | expression tag |
| His 404 | - | expression tag |
| His 405 | - | expression tag |
| His 406 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 161642.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 414.5 | |
| All* | Total formula weight | 162057.4 |
