9O35
Crystal structure of DoxA in complex with daunorubicin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cytochrome P-450 monooxygenase DoxA | polymer | 425 | 46064.2 | 2 | UniProt (Q9ZAU3) Pfam (PF00067) | Streptomyces peucetius subsp. caesius ATCC 27952 | 13-deoxycarminomycin C-13 hydroxylase,13-deoxydaunorubicin C-13 hydroxylase,13-dihydrocarminomycin C-13 hydroxylase,13-dihydrodaunorubicin C-13 hydroxylase |
| 2 | C, E (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 3 | D, F (A, B) | DAUNOMYCIN | non-polymer | 527.5 | 2 | Chemie (DM1) | |||
| 4 | G (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 331 | Chemie (HOH) |
Sequence modifications
A, B: 9 - 422 (UniProt: Q9ZAU3)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Met 1 | - | expression tag |
| Ser 2 | - | expression tag |
| Gly 3 | - | expression tag |
| Glu 4 | - | expression tag |
| Ala 5 | - | expression tag |
| Pro 6 | - | expression tag |
| Arg 7 | - | expression tag |
| Val 8 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 92128.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 2384.1 | |
| All* | Total formula weight | 94512.5 |
