9NX2
Muscle-type nicotinic acetylcholine receptor bound to conotoxin ImII
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Acetylcholine receptor subunit alpha | polymer | 434 | 49869.9 | 2 | UniProt (P02710) | Tetronarce californica (Pacific electric ray) | |
| 2 | B (B) | Acetylcholine receptor subunit delta | polymer | 499 | 57455.5 | 1 | UniProt (P02718) | Tetronarce californica (Pacific electric ray) | |
| 3 | C (C) | Acetylcholine receptor subunit beta | polymer | 469 | 53731.8 | 1 | UniProt (P02712) | Tetronarce californica (Pacific electric ray) | |
| 4 | E (E) | Acetylcholine receptor subunit gamma | polymer | 489 | 56335.7 | 1 | UniProt (P02714) | Tetronarce californica (Pacific electric ray) | |
| 5 | F, G (F, G) | Alpha-conotoxin ImII | polymer | 13 | 1516.8 | 2 | UniProt (Q8I6R5) | Conus imperialis | Alpha-CTx ImII |
| 6 | H, M (H, M) | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G94626GC) | |||
| 7 | I (I) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
| 8 | J (J) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 9 | K (K) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 10 | L (L) | alpha-D-mannopyranose-(1-2)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 1 | In PDB GlyTouCan (G99516QU) | |||
| 11 | N, P (A, D) | 2-[(AMINOCARBONYL)OXY]-N,N,N-TRIMETHYLETHANAMINIUM | non-polymer | 147.2 | 2 | Chemie (CCE) | |||
| 12 | O, Q (B, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 13 | R, S, T (A, B, D) | water | water | 18.0 | 5 | Chemie (HOH) |
Sequence modifications
A, D: 1 - 434 (UniProt: P02710)
F, G: 1 - 12 (UniProt: Q8I6R5)
| PDB | External Database | Details |
|---|---|---|
| Lys 430 | Leu 454 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Nh2 13 | - | amidation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 270296.4 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 4816.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 736.8 | |
| All* | Total formula weight | 275849.6 |
