9NX2
Muscle-type nicotinic acetylcholine receptor bound to conotoxin ImII
Functional Information from PROSITE/UniProt
| site_id | PS00236 |
| Number of Residues | 15 |
| Details | NEUROTR_ION_CHANNEL Neurotransmitter-gated ion-channels signature. CtIkVmyFPfDwqnC |
| Chain | Residue | Details |
| C | CYS128-CYS142 | |
| E | CYS128-CYS142 | |
| A | CYS128-CYS142 | |
| B | CYS130-CYS144 |
| site_id | PS60014 |
| Number of Residues | 11 |
| Details | ALPHA_CONOTOXIN Alpha-conotoxin family signature. CCSdRRCR....WRC |
| Chain | Residue | Details |
| F | CYS2-CYS12 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 635 |
| Details | Topological domain: {"description":"Extracellular"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 308 |
| Details | Transmembrane: {"description":"Helical"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"2742850","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"6585820","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"2742850","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 215 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 81 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 22 |
| Details | Peptide: {"description":"Alpha-conotoxin ImII","featureId":"PRO_0000034878","evidences":[{"source":"PubMed","id":"12384509","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Cysteine amide","evidences":[{"source":"PubMed","id":"12384509","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
