9NN9
ISG15 complexed with nanobody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Ubiquitin-like protein ISG15 | polymer | 165 | 18150.7 | 3 | UniProt (P05161) Pfam (PF00240) | Homo sapiens (human) | Interferon-induced 15 kDa protein,Interferon-induced 17 kDa protein,IP17,Ubiquitin cross-reactive protein,hUCRP |
| 2 | B, D, F (B, D, F) | Nanobody | polymer | 149 | 16317.9 | 3 | Vicugna pacos | ||
| 3 | G, I, J (A, D, F) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | H (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | K, L, M, N, O... (A, B, C, D, E...) | water | water | 18.0 | 158 | Chemie (HOH) |
Sequence modifications
A, C, E: 1 - 157 (UniProt: P05161)
| PDB | External Database | Details |
|---|---|---|
| Ser 78 | Cys 78 | engineered mutation |
| Ser 158 | - | expression tag |
| Ser 159 | - | expression tag |
| His 160 | - | expression tag |
| His 161 | - | expression tag |
| His 162 | - | expression tag |
| His 163 | - | expression tag |
| His 164 | - | expression tag |
| His 165 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 103405.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 282.3 | |
| All* | Total formula weight | 103688.0 |
