9NJA
Computationally optimized broadly reactive influenza B hemagglutinin BC2 bound by antibody #46
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G (L, K, P) | Fab A Light Chain | polymer | 218 | 23206.6 | 3 | Homo sapiens | ||
| 2 | B, E, H (H, J, Q) | Fab A Heavy Chain | polymer | 233 | 24846.0 | 3 | Homo sapiens | ||
| 3 | C, F, I (A, B, C) | Hemagglutinin | polymer | 530 | 57375.2 | 3 | UniProt (P17504) | Influenza B virus | |
| 4 | J, K, L (D, E, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 5 | M, N, O, P, Q... (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) |
Sequence modifications
A, B, C: 1 - 523 (UniProt: P17504)
| PDB | External Database | Details |
|---|---|---|
| Arg 88 | Lys 103 | conflict |
| Asn 116 | His 131 | conflict |
| Lys 129 | Thr 144 | conflict |
| Arg 136 | Lys 151 | conflict |
| Ile 137 | Val 152 | conflict |
| Thr 199 | Ala 214 | conflict |
| Lys 202 | Val 217 | conflict |
| Thr 235 | Ala 250 | conflict |
| Val 262 | Thr 277 | conflict |
| Ala 293 | Arg 308 | conflict |
| Ser 524 | - | expression tag |
| Gly 525 | - | expression tag |
| Arg 526 | - | expression tag |
| Leu 527 | - | expression tag |
| Val 528 | - | expression tag |
| Pro 529 | - | expression tag |
| Arg 530 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 316283.5 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1273.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1327.2 | |
| All* | Total formula weight | 318884.0 |
