9NB5
Cryo-EM structure of the autoinhibitory CD163 trimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Scavenger receptor cysteine-rich type 1 protein M130 | polymer | 1012 | 109731.6 | 3 | UniProt (Q86VB7) Pfam (PF00530) | Homo sapiens (human) | Hemoglobin scavenger receptor |
| 2 | AA, BA, CA, D, E... (C, A, B) | CALCIUM ION | non-polymer | 40.1 | 20 | Chemie (CA) | Homo sapiens (human) | Hemoglobin scavenger receptor | |
| 3 | DA, EA, FA, K, L... (C, A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) | Homo sapiens (human) | Hemoglobin scavenger receptor |
Sequence modifications
A, B, C: 42 - 1045 (UniProt: Q86VB7)
| PDB | External Database | Details |
|---|---|---|
| His 1046 | - | expression tag |
| His 1047 | - | expression tag |
| His 1048 | - | expression tag |
| His 1049 | - | expression tag |
| His 1050 | - | expression tag |
| His 1051 | - | expression tag |
| His 1052 | - | expression tag |
| His 1053 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 329194.7 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 2792.4 | |
| All* | Total formula weight | 331987.1 |
