9NAL
Cryo-EM structure of ternary complex of human phosphoribosylglycinamidine synthase with the intermediate (iminophosphate) and ADP bound at the synthase site.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phosphoribosylformylglycinamidine synthase | polymer | 1369 | 148495.7 | 1 | UniProt (O15067) | Homo sapiens (human) | FGAM synthase,FGAMS,Formylglycinamide ribonucleotide amidotransferase,FGAR amidotransferase,FGAR-AT,Formylglycinamide ribotide amidotransferase,Phosphoribosylformylglycineamide amidotransferase |
| 2 | B, C (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 3 | D (A) | N-[2-formamido-1-(phosphonooxy)ethylidene]-5-O-phosphono-beta-D-ribofuranosylamine | non-polymer | 394.2 | 1 | Chemie (A1B7I) | |||
| 4 | E, F, G (A) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 5 | H (A) | water | water | 18.0 | 96 | Chemie (HOH) |
Sequence modifications
A: 1 - 1338 (UniProt: O15067)
| PDB | External Database | Details |
|---|---|---|
| Thr 1339 | - | expression tag |
| Arg 1340 | - | expression tag |
| Thr 1341 | - | expression tag |
| Arg 1342 | - | expression tag |
| Pro 1343 | - | expression tag |
| Leu 1344 | - | expression tag |
| Glu 1345 | - | expression tag |
| Gln 1346 | - | expression tag |
| Lys 1347 | - | expression tag |
| Leu 1348 | - | expression tag |
| Ile 1349 | - | expression tag |
| Ser 1350 | - | expression tag |
| Glu 1351 | - | expression tag |
| Glu 1352 | - | expression tag |
| Asp 1353 | - | expression tag |
| Leu 1354 | - | expression tag |
| Ala 1355 | - | expression tag |
| Ala 1356 | - | expression tag |
| Asn 1357 | - | expression tag |
| Asp 1358 | - | expression tag |
| Ile 1359 | - | expression tag |
| Leu 1360 | - | expression tag |
| Asp 1361 | - | expression tag |
| Tyr 1362 | - | expression tag |
| Lys 1363 | - | expression tag |
| Asp 1364 | - | expression tag |
| Asp 1365 | - | expression tag |
| Asp 1366 | - | expression tag |
| Asp 1367 | - | expression tag |
| Lys 1368 | - | expression tag |
| Val 1369 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 148495.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1321.5 | |
| All* | Total formula weight | 149817.2 |
