9N20

Structure of C3d Bound to a Fragment of FHR-2 and S. aureus Efb-C

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Complement C3dg fragment	polymer	297	33143.9	1	UniProt (P01024) Pfam (PF07678)	Homo sapiens (human)
2	B (C)	Fibrinogen-binding protein	polymer	75	8597.0	1	UniProt (P68799)	Staphylococcus aureus subsp. aureus Mu50
3	C (B)	Complement factor H-related protein 2	polymer	131	14662.5	1	UniProt (P36980) Pfam (PF00084)	Homo sapiens (human)	FHR-2,DDESK59,H factor-like 3,H factor-like protein 2

Sequence modifications

A: 996 - 1287 (UniProt: P01024)

PDB	External Database	Details
Gly 991	-	expression tag
Ser 992	-	expression tag
Arg 993	-	expression tag
Ser 994	-	expression tag
Thr 995	-	expression tag
Ala 1010	Cys 1010	engineered mutation

C: 94 - 165 (UniProt: P68799)

PDB	External Database	Details
Gly 91	-	expression tag
Ser 92	-	expression tag
Thr 93	-	expression tag

B: 145 - 270 (UniProt: P36980)

PDB	External Database	Details
Gly 140	-	expression tag
Ser 141	-	expression tag
Thr 142	-	expression tag
Gly 143	-	expression tag
Ser 144	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	56403.4
All*	Total formula weight	56403.4

*Water molecules are not included.