9N1F
Crystal Structure of the Ark2C-Ubc13~Ub-Mms2 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | E3 ubiquitin-protein ligase ARK2C | polymer | 87 | 9859.2 | 1 | UniProt (Q6ZSG1) Pfam (PF13639) | Homo sapiens (human) | RING finger protein 165,RNF165 |
| 2 | B (B) | Ubiquitin-conjugating enzyme E2 N | polymer | 157 | 17566.1 | 1 | UniProt (P61088) Pfam (PF00179) | Homo sapiens (human) | Bendless-like ubiquitin-conjugating enzyme,E2 ubiquitin-conjugating enzyme N,Ubc13,UbcH13,Ubiquitin carrier protein N,Ubiquitin-protein ligase N |
| 3 | C (C) | Ubiquitin-conjugating enzyme E2 variant 2 | polymer | 145 | 16364.7 | 1 | UniProt (Q15819) Pfam (PF00179) | Homo sapiens (human) | DDVit 1,Enterocyte differentiation-associated factor 1,EDAF-1,Enterocyte differentiation-promoting factor 1,EDPF-1,MMS2 homolog,Vitamin D3-inducible protein |
| 4 | D (D) | Ubiquitin | polymer | 76 | 8576.8 | 1 | UniProt (P0CG48) Pfam (PF00240) | Homo sapiens (human) | |
| 5 | E, F (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | G, H, I (A, B, C) | water | water | 18.0 | 64 | Chemie (HOH) |
Sequence modifications
A: 255 - 346 (UniProt: Q6ZSG1)
B: 1 - 152 (UniProt: P61088)
C: 1 - 145 (UniProt: Q15819)
| PDB | External Database | Details |
|---|---|---|
| Gly 250 | - | expression tag |
| Pro 251 | - | expression tag |
| Leu 252 | - | expression tag |
| Gly 253 | - | expression tag |
| Ser 254 | - | expression tag |
| - | Arg 273 | deletion |
| - | Arg 274 | deletion |
| - | Pro 275 | deletion |
| - | Gln 276 | deletion |
| - | Asp 277 | deletion |
| - | Gly 278 | deletion |
| - | Lys 279 | deletion |
| - | Gly 280 | deletion |
| - | Lys 281 | deletion |
| - | Lys 282 | deletion |
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Lys 87 | Cys 87 | engineered mutation |
| Thr 92 | Lys 92 | engineered mutation |
| Gln 94 | Lys 94 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 32 | Ser 32 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 52366.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 52497.7 |
