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9MZY

Crystal structure of human RIPK1 with Compound 22

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Receptor-interacting serine/threonine-protein kinase 1polymer28732665.82UniProt (Q13546)
Pfam (PF07714)
Homo sapiens (human)Cell death protein RIP,Receptor-interacting protein 1,RIP-1
2C, H
(A, B)
1-[(2S,5S)-2,3-dihydro-2,5-methano-1,4-benzoxazepin-4(5H)-yl]-3,3-difluoro-2,2-dimethylpropan-1-onenon-polymer281.32Chemie (A1BU6)
3D, E, F, J
(A, B)
IODIDE IONnon-polymer126.94Chemie (IOD)
4G
(A)
GLYCINEnon-polymer75.11Chemie (GLY)
5I
(B)
CHLORIDE IONnon-polymer35.51Chemie (CL)
6K, L
(A, B)
waterwater18.069Chemie (HOH)
Sequence modifications
A, B: 8 - 294 (UniProt: Q13546)
PDBExternal DatabaseDetails
Ala 34Cys 34conflict
Ala 127Cys 127conflict
Ala 233Cys 233conflict
Ala 240Cys 240conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight65331.6
Non-Polymers*Number of molecules8
Total formula weight1180.7
All*Total formula weight66512.3
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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