9MX8
Crystal structure of the DNA binding domain of FLI1 in complex with a DNA containing three contiguous GGAA sites
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, C, D) | Friend leukemia integration 1 transcription factor | polymer | 121 | 13862.6 | 3 | UniProt (Q01543) Pfam (PF00178) | Homo sapiens (human) | Proto-oncogene Fli-1,Transcription factor ERGB |
| 2 | D (E) | DNA (5'-D(P*GP*AP*CP*CP*GP*GP*AP*AP*GP*GP*AP*AP*GP*GP*AP*AP*GP*TP*G)-3') | polymer | 19 | 5992.9 | 1 | synthetic construct | ||
| 3 | E (F) | DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*TP*TP*CP*CP*TP*TP*CP*CP*GP*GP*TP*C)-3') | polymer | 19 | 5658.6 | 1 | synthetic construct |
Sequence modifications
A, C, D: 259 - 375 (UniProt: Q01543)
| PDB | External Database | Details |
|---|---|---|
| Gly 255 | - | expression tag |
| Pro 256 | - | expression tag |
| His 257 | - | expression tag |
| Met 258 | - | expression tag |
| Ala 362 | Phe 362 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 53239.3 | |
| All* | Total formula weight | 53239.3 |
