9MWY
Crystal structure of the DNA binding domain of FLI1 in complex with a DNA containing four contiguous GGAA sites
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, D, C, L) | Friend leukemia integration 1 transcription factor | polymer | 145 | 16710.8 | 4 | UniProt (Q01543) Pfam (PF00178) | Homo sapiens (human) | Proto-oncogene Fli-1,Transcription factor ERGB |
| 2 | E (G) | 25-mer DNA containing four contiguous GGAA sites, bottom strand | polymer | 25 | 7896.1 | 1 | synthetic construct | ||
| 3 | F (H) | 25-mer DNA containing four contiguous GGAA sites, top strand | polymer | 25 | 7463.8 | 1 | synthetic construct | ||
| 4 | G, H (A, C) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) |
Sequence modifications
A, D, C, L: 259 - 399 (UniProt: Q01543)
| PDB | External Database | Details |
|---|---|---|
| Gly 255 | - | expression tag |
| Pro 256 | - | expression tag |
| His 257 | - | expression tag |
| Met 258 | - | expression tag |
| Ala 362 | Phe 362 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 82202.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 46.0 | |
| All* | Total formula weight | 82248.9 |
