9MW4
Co-crystal structure of feline coronavirus UU23 main protease with Pfizer intravenous compound PF-00835231
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ORF1ab polyprotein | polymer | 300 | 32727.1 | 1 | UniProt (D3KDL2) Pfam (PF05409) | Feline alphacoronavirus 1 | |
| 2 | B (A) | N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide | non-polymer | 474.6 | 1 | Chemie (V2M) | |||
| 3 | C, D, F (A) | ACETIC ACID | non-polymer | 60.1 | 3 | Chemie (ACY) | |||
| 4 | E, I (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 5 | G, H, J, L (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 6 | K, M, N (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 7 | O (A) | water | water | 18.0 | 433 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32727.1 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1609.8 | |
| All* | Total formula weight | 34336.9 |
