9MRT
Cryo-EM structure of the human TRPM4 channel in a calcium and PI(4,5)P2 bound open state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (B, A, C, D) | Transient receptor potential cation channel subfamily M member 4 | polymer | 1214 | 134456.5 | 4 | UniProt (Q8TD43) | Homo sapiens (human) | hTRPM4,Calcium-activated non-selective cation channel 1,Long transient receptor potential channel 4,LTrpC4,Melastatin-4 |
| 2 | E, H, K, N (B, A, C, D) | [(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate | non-polymer | 1047.1 | 4 | Chemie (PT5) | |||
| 3 | F, G, I, J, L... (B, A, C, D) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 537825.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 4509.0 | |
| All* | Total formula weight | 542334.9 |
