9MRT
Cryo-EM structure of the human TRPM4 channel in a calcium and PI(4,5)P2 bound open state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (B, A, C, D) | Transient receptor potential cation channel subfamily M member 4 | polymer | 1214 | 134456.5 | 4 | UniProt (Q8TD43) Pfam (PF18139) Pfam (PF25508) Pfam (PF00520) | Homo sapiens (human) | hTRPM4,Calcium-activated non-selective cation channel 1,Long transient receptor potential channel 4,LTrpC4,Melastatin-4 |
| 2 | E, H, K, N (B, A, C, D) | [(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate | non-polymer | 1047.1 | 4 | Chemie (PT5) PubChem (21584053) PubChem (24742075) PubChem (25021172) PubChem (46891800) PubChem (53480261) PubChem (49867532) PubChem (53731018) PubChem (5497157) PubChem (74343116) PubChem (644093) PubChem (88368868) PubChem (101103400) PubChem (101127471) PubChem (137349554) PubChem (146672970) PubChem (162802760) PubChem (137349667) PubChem (155387720) PubChem (177693253) | |||
| 3 | F, G, I, J, L... (B, A, C, D) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) PubChem (271) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 537825.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 4509.0 | |
| All* | Total formula weight | 542334.9 |
