9MLC
Pol II-DSIF-SPT6-PAF1c-TFIIS-IWS1-ELOF1-LEDGF-nucleosome activated elongation complex Composite map T
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA-directed RNA polymerase II subunit RPB1 | polymer | 1984 | 218920.6 | 1 | Sus scrofa (pig) | ||
| 2 | B (B) | DNA-directed RNA polymerase subunit beta | polymer | 1300 | 147938.6 | 1 | UniProt (I3LGP4) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF04566) Pfam (PF04567) Pfam (PF00562) Pfam (PF04560) | Sus scrofa (pig) | |
| 3 | C (C) | DNA-directed RNA polymerase II subunit RPB3 | polymer | 275 | 31439.1 | 1 | UniProt (A0A481DF93) | Sus scrofa (pig) | |
| 4 | D (D) | RPOL4c domain-containing protein | polymer | 184 | 20962.6 | 1 | UniProt (A0A8D1GCS3) | Sus scrofa (pig) | |
| 5 | E (E) | DNA-directed RNA polymerase II subunit E | polymer | 210 | 24644.3 | 1 | UniProt (A0A4X1VTX4) | Sus scrofa (pig) | RPB5 |
| 6 | F (F) | DNA-directed RNA polymerases I, II, and III subunit RPABC2 | polymer | 127 | 14477.0 | 1 | UniProt (A0A4X1VEK9) Pfam (PF01192) | Sus scrofa (pig) | DNA-directed RNA polymerase II subunit F,RPB6 homolog |
| 7 | G (G) | DNA-directed RNA polymerase II subunit RPB7 | polymer | 172 | 19314.3 | 1 | UniProt (A0A4X1VKG7) | Sus scrofa (pig) | |
| 8 | H (H) | DNA-directed RNA polymerases I, II, and III subunit RPABC3 | polymer | 150 | 17162.3 | 1 | UniProt (A0A8D1AQR7) | Sus scrofa (pig) | |
| 9 | I (I) | DNA-directed RNA polymerase II subunit RPB9 | polymer | 125 | 14541.2 | 1 | UniProt (P60899) Pfam (PF01096) Pfam (PF02150) | Sus scrofa (pig) | RNA polymerase II subunit B9,DNA-directed RNA polymerase II subunit I,RNA polymerase II 14.5 kDa subunit,RPB14.5 |
| 10 | J (J) | DNA-directed RNA polymerases I, II, and III subunit RPABC5 | polymer | 67 | 7655.1 | 1 | UniProt (A0A8W4F9W9) Pfam (PF01194) | Sus scrofa (pig) | |
| 11 | K (K) | RNA polymerase II subunit J | polymer | 117 | 13310.3 | 1 | UniProt (A0A8D0TE17) | Sus scrofa (pig) | |
| 12 | L (L) | RNA polymerase II subunit K | polymer | 58 | 7018.2 | 1 | UniProt (A0A4X1TRS6) Pfam (PF03604) | Sus scrofa (pig) | |
| 13 | M (M) | Transcription elongation factor SPT6 | polymer | 1726 | 199330.7 | 1 | Homo sapiens | ||
| 14 | N (N) | DNA (194-MER) | polymer | 206 | 63984.7 | 1 | synthetic construct | ||
| 15 | O (O) | Transcription elongation factor 1 homolog | polymer | 83 | 9475.9 | 1 | UniProt (P60002) Pfam (PF05129) | Homo sapiens (human) | |
| 16 | P (P) | RNA (5'-R(P*UP*UP*UP*GP*GP*UP*GP*UP*GP*UP*CP*UP*GP*GP*GP*UP*GP*GP*UP*G)-3') | polymer | 39 | 12544.3 | 1 | synthetic construct | ||
| 17 | Q (Q) | RNA polymerase-associated protein CTR9 homolog | polymer | 1173 | 133715.4 | 1 | UniProt (Q6PD62) Pfam (PF13374) Pfam (PF13181) | Homo sapiens (human) | SH2 domain-binding protein 1 |
| 18 | R (R) | RNA polymerase-associated protein RTF1 homolog | polymer | 710 | 80460.8 | 1 | Homo sapiens | ||
| 19 | S (S) | Transcription elongation factor A protein 1 | polymer | 301 | 34022.7 | 1 | UniProt (P23193) Pfam (PF08711) Pfam (PF07500) Pfam (PF01096) | Homo sapiens (human) | Transcription elongation factor S-II protein 1, Transcription elongation factor TFIIS.o |
| 20 | T (T) | DNA (194-MER) | polymer | 215 | 66042.1 | 1 | synthetic construct | ||
| 21 | U (U) | RNA polymerase-associated protein LEO1 | polymer | 666 | 75514.2 | 1 | UniProt (Q8WVC0) Pfam (PF04004) | Homo sapiens (human) | Replicative senescence down-regulated leo1-like protein |
| 22 | V (V) | RNA polymerase II-associated factor 1 homolog | polymer | 531 | 60052.7 | 1 | UniProt (Q8N7H5) Pfam (PF03985) | Homo sapiens (human) | hPAF1,Pancreatic differentiation protein 2 |
| 23 | W (W) | WDR61 | polymer | 305 | 33617.5 | 1 | UniProt (Q9GZS3) Pfam (PF00400) | Homo sapiens (human) | |
| 24 | X (X) | Parafibromin | polymer | 531 | 60673.5 | 1 | UniProt (Q6P1J9) Pfam (PF16050) Pfam (PF05179) | Homo sapiens (human) | Cell division cycle protein 73 homolog,Hyperparathyroidism 2 protein |
| 25 | Y (Y) | Transcription elongation factor SPT4 | polymer | 117 | 13210.2 | 1 | UniProt (P63272) Pfam (PF06093) | Homo sapiens (human) | hSPT4,DRB sensitivity-inducing factor 14 kDa subunit,DSIF p14,DRB sensitivity-inducing factor small subunit,DSIF small subunit |
| 26 | Z (Z) | Transcription elongation factor SPT5 | polymer | 1087 | 121145.5 | 1 | UniProt (O00267) Pfam (PF11942) Pfam (PF03439) Pfam (PF00467) Pfam (PF23037) Pfam (PF23288) Pfam (PF23287) | Homo sapiens (human) | hSPT5,DRB sensitivity-inducing factor 160 kDa subunit,DSIF p160,DRB sensitivity-inducing factor large subunit,DSIF large subunit,Tat-cotransactivator 1 protein,Tat-CT1 protein |
| 27 | AA (i) | Protein IWS1 homolog | polymer | 819 | 92094.8 | 1 | UniProt (Q96ST2) Pfam (PF08711) | Homo sapiens (Human) | IWS1-like protein |
| 28 | BA, CA, EA, FA, GA... (A, B, C, I, J...) | ZINC ION | non-polymer | 65.4 | 10 | Chemie (ZN) | Xenopus laevis | ||
| 29 | DA (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | Xenopus laevis |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 27 |
| Total formula weight | 1593268.5 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 678.4 | |
| All* | Total formula weight | 1593946.9 |
