9MJY
Crystal structure of WRN helicase with bound allosteric compound 1
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN | polymer | 443 | 50480.9 | 1 | UniProt (Q14191) Pfam (PF00270) Pfam (PF00271) Pfam (PF16124) | Homo sapiens (human) | DNA helicase,RecQ-like type 3,RecQ protein-like 2,Werner syndrome protein |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C, D (A) | (3-{[4-(trifluoromethyl)phenyl]carbamoyl}furan-2-yl)acetic acid | non-polymer | 313.2 | 2 | Chemie (A1BL0) | |||
| 4 | E, F, G, H, O (A) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 5 | I, K, L, M, N (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 6 | J (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 7 | P (A) | water | water | 18.0 | 257 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 50480.9 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1257.6 | |
| All* | Total formula weight | 51738.5 |
