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9MJX

Crystal structure of WRN helicase with bound allosteric fragment 4

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRNpolymer44350480.91UniProt (Q14191)
Pfam (PF00270)
Pfam (PF00271)
Pfam (PF16124)
Homo sapiens (human)DNA helicase,RecQ-like type 3,RecQ protein-like 2,Werner syndrome protein
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
(4R)-8-amino-2-cyclopropylimidazo[1,2-a]pyridine-6-carboxylic acidnon-polymer217.21Chemie (A1BL4)
4D
(A)
5,6-diaminopyridine-3-carboxylic acidnon-polymer153.11Chemie (A1BL5)
5E, F
(A)
SULFATE IONnon-polymer96.12Chemie (SO4)
6G, H, I
(A)
CHLORIDE IONnon-polymer35.53Chemie (CL)
7J, K, L, M, N
(A)
1,2-ETHANEDIOLnon-polymer62.15Chemie (EDO)
8O
(A)
waterwater18.0227Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight50480.9
Non-Polymers*Number of molecules13
Total formula weight1044.6
All*Total formula weight51525.5
*Water molecules are not included.

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PDB entries from 2026-02-11

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