9MI0
61-12A01 Fab in complex with HIV-1 GT1.1 v4.1 SOSIP Env trimer and RM20A3 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, G, M (H, K, P) | 61_12A01 heavy chain Fv | polymer | 123 | 13989.6 | 3 | Homo sapiens | ||
| 2 | B, H, N (L, N, R) | 61_12A01 kappa chain Fv | polymer | 104 | 11199.4 | 3 | Homo sapiens | ||
| 3 | C, I, O (G, J, O) | RM20A3 heavy chain Fv | polymer | 125 | 13511.1 | 3 | Macaca mulatta | ||
| 4 | D, J, P (I, M, Q) | RM20A3 light chain Fv | polymer | 128 | 13508.8 | 3 | Macaca mulatta | ||
| 5 | E, K, Q (A, C, E) | GT1.1 v4.1 SOSIP gp120 | polymer | 509 | 57275.5 | 3 | Human immunodeficiency virus 1 | ||
| 6 | F, L, R (B, D, F) | Envelope glycoprotein gp160 | polymer | 153 | 17146.5 | 3 | UniProt (Q2N0S6) Pfam (PF00517) UniProt (by SIFTS) (D0PUM0) | Human immunodeficiency virus 1 | |
| 7 | AA, BA, CA, DA, FA... (a, b, c, d, f...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 12 | In PDB GlyTouCan (G42666HT) | |||
| 8 | EA, U, Z (e, U, Z) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G81315DD) | |||
| 9 | AB, BB, CB, DB, EB... (E, F, A, B, C...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 24 | Chemie (NAG) |
Sequence modifications
B, D, F: 512 - 664 (UniProt: Q2N0S6)
| PDB | External Database | Details |
|---|---|---|
| Pro 559 | Ile 556 | conflict |
| Cys 605 | Thr 602 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 18 |
| Total formula weight | 379892.8 | |
| Branched | Number of molecules | 15 |
| Total formula weight | 7338.9 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 5309.0 | |
| All* | Total formula weight | 392540.7 |
