9MFL

Structure of zebrafish OTOP1 in nanodisc in the presence of inhibitor C11

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Proton channel OTOP1	polymer	587	65817.0	2	UniProt (Q7ZWK8) Pfam (PF03189)	Danio rerio (zebrafish)	Otopetrin-1
2	C, D, G, H (A, B)	CHOLESTEROL HEMISUCCINATE	non-polymer		486.7	4	Chemie (Y01) PubChem (16219150) PubChem (22210610) PubChem (65082) PubChem (45489984) PubChem (363416) PubChem (60078761) PubChem (500055) PubChem (73440805) PubChem (57163942) PubChem (89891013) PubChem (99567468) PubChem (124427194) PubChem (124897021) PubChem (124897020) PubChem (10005657) PubChem (130340716) PubChem (99567469) PubChem (11969853) PubChem (137392566) PubChem (137496323) PubChem (124301053) PubChem (124302591) PubChem (124303794) PubChem (124421343) PubChem (124427195) PubChem (13301926) PubChem (13301927) PubChem (124914595) PubChem (124914596) PubChem (155804219) PubChem (169132514) PubChem (131705526) PubChem (137332121) PubChem (137496357) PubChem (146157332) PubChem (154929912) PubChem (155199678) PubChem (156327905) PubChem (156426247) PubChem (156516588) PubChem (166979870) PubChem (167024614) PubChem (169132513) PubChem (170117245) PubChem (172400028)
3	E, F, I, J (A, B)	(3beta,5beta,14beta,17alpha)-cholestan-3-ol	non-polymer		388.7	4	Chemie (QNJ) PubChem (16219103) PubChem (18608608) PubChem (18640090) PubChem (18655846) PubChem (3240) PubChem (21587537) PubChem (23425834) PubChem (44135456) PubChem (44206410) PubChem (17750988) PubChem (91465) PubChem (50990034) PubChem (50990085) PubChem (369314) PubChem (59006269) PubChem (45044206) PubChem (60127880) PubChem (66829181) PubChem (68017478) PubChem (68024043) PubChem (68229148) PubChem (68315615) PubChem (68381473) PubChem (68381765) PubChem (70574297) PubChem (70575287) PubChem (70577549) PubChem (56840784) PubChem (637621) PubChem (59720718) PubChem (2754261) PubChem (68652050) PubChem (70575638) PubChem (90070174) PubChem (90180497) PubChem (6665) PubChem (66066) PubChem (221122) PubChem (70792447) PubChem (71016634) PubChem (124427190) PubChem (7173417) PubChem (7224987) PubChem (125035670) PubChem (6432369) PubChem (6432508) PubChem (6432729) PubChem (10916096) PubChem (11003628) PubChem (6708730) PubChem (6710623) PubChem (6710664) PubChem (99565216) PubChem (11406610) PubChem (7121446) PubChem (7121447) PubChem (7157118) PubChem (7173418) PubChem (7173419) PubChem (9800473) PubChem (11881063) PubChem (12305482) PubChem (10992748) PubChem (11036532) PubChem (124362921) PubChem (124439990) PubChem (11881060) PubChem (11881061) PubChem (11881062) PubChem (11888198) PubChem (11888199) PubChem (11888200) PubChem (12158506) PubChem (12305464) PubChem (12305465) PubChem (12305467) PubChem (12305468) PubChem (12305478) PubChem (12305480) PubChem (12305488) PubChem (124907351) PubChem (146616531) PubChem (125035667) PubChem (125035668) PubChem (125035669) PubChem (162919369) PubChem (167169618) PubChem (129017051) PubChem (129628062) PubChem (134762760) PubChem (135086371) PubChem (135240116) PubChem (138633309) PubChem (138756164) PubChem (142281450) PubChem (143806476) PubChem (144349392) PubChem (145303991) PubChem (145429358) PubChem (145543482) PubChem (154831865) PubChem (162658977) PubChem (162919370) PubChem (162919371) PubChem (162919372) PubChem (162919373) PubChem (162919374) PubChem (162919375) PubChem (163918475) PubChem (164665230) PubChem (168433505) PubChem (168856344) PubChem (169728330) PubChem (170325819) PubChem (170924116) PubChem (171039425) PubChem (174953350)

Sequence modifications

A, B: 2 - 586 (UniProt: Q7ZWK8)

PDB	External Database	Details
Gly 0	-	expression tag
Pro 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	131634.0
Non-Polymers*	Number of molecules	8
	Total formula weight	3501.6
All*	Total formula weight	135135.6

*Water molecules are not included.