9MFG
Complex of IL23 receptor and VHH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Interleukin-23 receptor | polymer | 304 | 35286.9 | 4 | UniProt (Q5VWK5) | Homo sapiens (human) | IL-23 receptor,IL-23R |
| 2 | E, F, G, H (E, F, G, H) | VHH | polymer | 120 | 13138.5 | 4 | Lama glama | ||
| 3 | I, T (I, T) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G21290RB) | |||
| 4 | J, N, Q, R, U (J, N, Q, R, U) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 5 | In PDB GlyTouCan (G42666HT) | |||
| 5 | K, O (K, O) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-3)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 2 | In PDB | |||
| 6 | L, P, S (L, P, S) | alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 3 | In PDB | |||
| 7 | M (M) | alpha-D-mannopyranose-(1-3)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 529.5 | 1 | In PDB | |||
| 8 | AA, V, W, Y, Z (D, A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
| 9 | BA, CA, DA, HA, X (D, G, A) | THIOCYANATE ION | non-polymer | 58.1 | 5 | Chemie (SCN) | |||
| 10 | EA (E) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 11 | FA, GA (E, F) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 12 | IA, JA, KA, LA, MA... (A, B, C, D, E...) | water | water | 18.0 | 90 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 25 - 317 (UniProt: Q5VWK5)
| PDB | External Database | Details |
|---|---|---|
| Gly 23 | - | expression tag |
| Ser 24 | - | expression tag |
| Gly 318 | - | expression tag |
| Asn 319 | - | expression tag |
| Ser 320 | - | expression tag |
| His 321 | - | expression tag |
| His 322 | - | expression tag |
| His 323 | - | expression tag |
| His 324 | - | expression tag |
| His 325 | - | expression tag |
| His 326 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 193701.6 | |
| Branched | Number of molecules | 13 |
| Total formula weight | 7456.0 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1680.7 | |
| All* | Total formula weight | 202838.3 |
