9MEZ
Crystal structure of MRAS(GDP) bound to LZTR1(Kelch domain)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G, I (A, C, E, G, I) | Ras-related protein M-Ras | polymer | 182 | 20780.7 | 5 | UniProt (O14807) Pfam (PF00071) | Homo sapiens (human) | Ras-related protein R-Ras3 |
| 2 | B, D, F, H, J (B, D, F, H, J) | Leucine-zipper-like transcriptional regulator 1 | polymer | 322 | 36592.1 | 5 | UniProt (Q8N653) Pfam (PF13418) Pfam (PF13415) Pfam (PF01344) | Homo sapiens (human) | LZTR-1 |
| 3 | K, N, Q, T, X (A, C, E, G, I) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 5 | Chemie (GDP) | |||
| 4 | L, O, R, U, Y (A, C, E, G, I) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
| 5 | M (A) | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
| 6 | P, S, W (D, E, H) | MALONIC ACID | non-polymer | 104.1 | 3 | Chemie (MLA) | |||
| 7 | V (G) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 8 | AA, BA, CA, Z (C, E, G, A) | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
A, C, E, G, I: 1 - 181 (UniProt: O14807)
B, D, F, H, J: 50 - 383 (UniProt: Q8N653)
B, D, F, H, J: 384 - 422 (UniProt: Q8N653)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 49 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 286863.8 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 2754.8 | |
| All* | Total formula weight | 289618.6 |
