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9MEY

Crystal structure of RIT1(GDP) bound to LZTR1(Kelch domain)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
GTP-binding protein Rit1polymer19722464.62UniProt (Q92963)
Pfam (PF00071)
Homo sapiens (human)Ras-like protein expressed in many tissues,Ras-like without CAAX protein 1
2B, D
(B, D)
Leucine-zipper-like transcriptional regulator 1polymer32236592.12UniProt (Q8N653)
Pfam (PF13418)
Pfam (PF13415)
Pfam (PF01344)
Homo sapiens (human)LZTR-1
3E, G
(A, C)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.22Chemie (GDP)
4F, H
(A, C)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
5I, J
(A, C)
waterwater18.09Chemie (HOH)
Sequence modifications
A, C: 2 - 197 (UniProt: Q92963)
PDBExternal DatabaseDetails
Gly 1-expression tag
B, D: 50 - 329 (UniProt: Q8N653)
PDBExternal DatabaseDetails
Gly 49-expression tag
B, D: 330 - 422 (UniProt: Q8N653)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight118113.3
Non-Polymers*Number of molecules4
Total formula weight935.0
All*Total formula weight119048.3
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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