9M8P

GPR3 dimer with antagonist AF64394

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Soluble cytochrome b562,G-protein coupled receptor 3	polymer	466	50446.4	2	UniProt (P0ABE7) UniProt (P46089) Pfam (PF07361) Pfam (PF00001)	Escherichia coli	Cytochrome b-562,ACCA orphan receptor
2	C, K (A, B)	(Z)-N-(2-hydroxyethyl)octadec-9-enamide	non-polymer		325.5	2	Chemie (5YM)
3	D, I, L, M (A, B)	1-DODECANOL	non-polymer		186.3	4	Chemie (1DO)
4	E, G, J, N (A, B)	(4Z)-oct-4-en-1-ol	non-polymer		128.2	4	Chemie (A1AJD)
5	F, H (A, B)	N-[(4-chloranyl-2-propan-2-yloxy-phenyl)methyl]-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine	non-polymer		393.9	2	Chemie (A1EM2)

Sequence modifications

A, B: -105 - 0 (UniProt: P0ABE7)

PDB	External Database	Details
Asp -123	-	expression tag
Tyr -122	-	expression tag
Lys -121	-	expression tag
Asp -120	-	expression tag
Asp -119	-	expression tag
Asp -118	-	expression tag
Asp -117	-	expression tag
Lys -116	-	expression tag
Leu -115	-	expression tag
Glu -114	-	expression tag
Val -113	-	expression tag
Leu -112	-	expression tag
Phe -111	-	expression tag
Gln -110	-	expression tag
Gly -109	-	expression tag
Pro -108	-	expression tag
Gly -107	-	expression tag
Ser -106	-	expression tag
Trp -99	Met 29	conflict
Ile -4	His 124	conflict
Leu 0	Arg 128	conflict

A, B: 1 - 330 (UniProt: P46089)

PDB	External Database	Details
Leu 331	-	expression tag
Glu 332	-	expression tag
His 333	-	expression tag
His 334	-	expression tag
His 335	-	expression tag
His 336	-	expression tag
His 337	-	expression tag
His 338	-	expression tag
His 339	-	expression tag
His 340	-	expression tag
His 341	-	expression tag
His 342	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	100892.8
Non-Polymers*	Number of molecules	12
	Total formula weight	2697.0
All*	Total formula weight	103589.7

*Water molecules are not included.