9M6G
the crystal structure of the Ca2+/CaM-CASK-CaMK-Mint1-CID complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peripheral plasma membrane protein CASK | polymer | 325 | 36682.5 | 1 | UniProt (O14936) Pfam (PF00069) | Homo sapiens (human) | hCASK,Calcium/calmodulin-dependent serine protein kinase,Protein lin-2 homolog |
| 2 | B (B) | Calmodulin-1 | polymer | 153 | 17150.8 | 1 | UniProt (P0DP29) Pfam (PF13499) | Rattus norvegicus (Norway rat) | |
| 3 | C (C) | Amyloid-beta A4 precursor protein-binding family A member 1 | polymer | 66 | 7734.7 | 1 | UniProt (O35430) | Rattus norvegicus (Norway rat) | Adapter protein X11alpha,Neuron-specific X11 protein,Neuronal Munc18-1-interacting protein 1,Mint-1 |
| 4 | D (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 5 | E (A) | MALONATE ION | non-polymer | 102.0 | 1 | Chemie (MLI) | |||
| 6 | F, G (B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 7 | H, I, J (A, B, C) | water | water | 18.0 | 363 | Chemie (HOH) |
Sequence modifications
A: 1 - 319 (UniProt: O14936)
B: 1 - 149 (UniProt: P0DP29)
C: 338 - 397 (UniProt: O35430)
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Phe 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 332 | - | expression tag |
| Pro 333 | - | expression tag |
| Gly 334 | - | expression tag |
| Ser 335 | - | expression tag |
| Glu 336 | - | expression tag |
| Phe 337 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 61568.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 688.4 | |
| All* | Total formula weight | 62256.4 |
