9M3O
Crystal structure of human pyruvate dehydrogenase kinase isoform 1 in complex with ATP competitive inhibitor 8
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial | polymer | 383 | 43788.9 | 1 | UniProt (Q15118) Pfam (PF10436) Pfam (PF02518) | Homo sapiens (human) | Pyruvate dehydrogenase kinase isoform 1,PDH kinase 1 |
| 2 | B (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 3 | C (A) | 6-fluoranyl-8-(methylamino)-N-(pyrimidin-5-ylmethyl)-9H-pyrido[2,3-b]indole-3-carboxamide | non-polymer | 350.4 | 1 | Chemie (A1EMR) | |||
| 4 | D, E, F (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | G (A) | water | water | 18.0 | 243 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43788.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 665.7 | |
| All* | Total formula weight | 44454.6 |
