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9M1M

Cryo-EM structure of the TBC-DEC-Arl2-alpha-beta-tubulin complex with GDP-AlFx

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(C)
Tubulin-specific chaperone Cpolymer34639300.11UniProt (Q15814)
Pfam (PF16752)
Pfam (PF07986)
Homo sapiens (human)Tubulin-folding cofactor C,CFC
2B
(D)
Tubulin-specific chaperone Dpolymer1192132752.51UniProt (Q9BTW9)
Pfam (PF23579)
Pfam (PF25767)
Pfam (PF12612)
Homo sapiens (human)Beta-tubulin cofactor D,tfcD,SSD-1,Tubulin-folding cofactor D
3C
(E)
Tubulin-specific chaperone Epolymer52759422.01UniProt (Q15813)
Pfam (PF01302)
Pfam (PF14560)
Homo sapiens (human)Tubulin-folding cofactor E
4D
(G)
ADP-ribosylation factor-like protein 2polymer18420904.01UniProt (P36404)
Pfam (PF00025)
Homo sapiens (human)
5E
(a)
Tubulin alpha-1B chainpolymer45150204.41UniProt (Q2XVP4)
Pfam (PF03953)
Pfam (PF00091)
Sus scrofa (pig)Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain
6F
(b)
Tubulin beta chainpolymer44449717.61UniProt (Q767L7)
Pfam (PF00091)
Pfam (PF03953)
Sus scrofa (pig)Tubulin beta-5 chain
7G
(G)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
PubChem (136073927)
PubChem (135398619)
PubChem (135402030)
PubChem (135431654)
PubChem (135566337)
PubChem (135760556)
PubChem (136026707)
PubChem (136053418)
PubChem (136663964)
PubChem (136664748)
PubChem (136759848)
PubChem (136759849)
PubChem (136759850)
PubChem (136836636)
PubChem (136847074)
PubChem (172898537)
8H
(G)
ALUMINUM FLUORIDEnon-polymer84.01Chemie (AF3)
PubChem (2124)
9I, K, M
(G, a, b)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
PubChem (888)
10J, L
(a, b)
GUANOSINE-5'-TRIPHOSPHATEnon-polymer523.22Chemie (GTP)
PubChem (177679032)
PubChem (135400627)
PubChem (135487750)
PubChem (136088935)
PubChem (136803486)
PubChem (135398633)
PubChem (135544356)
PubChem (135547949)
PubChem (135600366)
PubChem (135749822)
PubChem (136005188)
PubChem (136073923)
PubChem (136240914)
PubChem (136664747)
PubChem (136772743)
PubChem (136772744)
PubChem (136803487)
PubChem (137286749)
PubChem (164715984)
PubChem (171699466)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight352300.7
Non-Polymers*Number of molecules7
Total formula weight1646.5
All*Total formula weight353947.2
*Water molecules are not included.

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PDB entries from 2026-04-08

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