9LXE
Structure of compacted DNA-free MCM DH at 3.9 Angstroms resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, J (2, D) | DNA replication licensing factor MCM2 | polymer | 904 | 102034.1 | 2 | UniProt (P49736) Pfam (PF12619) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF23669) | Homo sapiens (human) | Minichromosome maintenance protein 2 homolog,Nuclear protein BM28 |
| 2 | B, H, I, K (3, B, C, E) | Isoform 2 of DNA replication licensing factor MCM3 | polymer | 853 | 96043.3 | 4 | UniProt (P25205) Pfam (PF17855) Pfam (PF23191) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) | Homo sapiens (human) | DNA polymerase alpha holoenzyme-associated protein P1,P1-MCM3,RLF subunit beta,p102 |
| 3 | C, L (4, F) | DNA replication licensing factor MCM4 | polymer | 863 | 96684.9 | 2 | UniProt (P33991) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF21128) | Homo sapiens (human) | CDC21 homolog,P1-CDC21 |
| 4 | D, N (5, H) | DNA replication licensing factor MCM5 | polymer | 734 | 82288.6 | 2 | UniProt (P33992) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF21933) | Homo sapiens (human) | CDC46 homolog,P1-CDC46 |
| 5 | E, M (6, G) | DNA replication licensing factor MCM6 | polymer | 821 | 93010.3 | 2 | UniProt (Q14566) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF18263) | Homo sapiens (human) | p105MCM |
| 6 | F, G (7, A) | DNA replication licensing factor MCM7 | polymer | 719 | 81411.9 | 2 | UniProt (P33993) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF24901) | Homo sapiens (human) | CDC47 homolog,P1.1-MCM3 |
| 7 | O, U (2, D) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 8 | P, Q, R, S, T... (3, 4, 6, 7, A...) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 8 | Chemie (ADP) |
Sequence modifications
5, H: 1 - 734 (UniProt: P33992)
| PDB | External Database | Details |
|---|---|---|
| Ala 601 | Asp 601 | conflict |
| Leu 602 | Arg 602 | conflict |
| Leu 603 | Arg 603 | conflict |
| Ala 604 | Ser 604 | conflict |
| Thr 652 | Ala 652 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 14 |
| Total formula weight | 1295032.6 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 4432.0 | |
| All* | Total formula weight | 1299464.6 |
