9LU1
protein structure of DDB1-DDA1-DET1-Ube2e2 bound to COP1 dimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, E) | E3 ubiquitin-protein ligase COP1 | polymer | 731 | 80569.2 | 2 | UniProt (Q8NHY2) | Homo sapiens (human) | Constitutive photomorphogenesis protein 1 homolog,hCOP1,RING finger and WD repeat domain protein 2,RING finger protein 200,RING-type E3 ubiquitin transferase RFWD2 |
| 2 | B (B) | DET1- and DDB1-associated protein 1 | polymer | 102 | 11855.3 | 1 | UniProt (Q9BW61) | Homo sapiens (human) | Placenta cross-immune reaction antigen 1,PCIA-1 |
| 3 | C (C) | Ubiquitin-conjugating enzyme E2 E2 | polymer | 201 | 22236.0 | 1 | UniProt (Q96LR5) | Homo sapiens (human) | E2 ubiquitin-conjugating enzyme E2,UbcH8,Ubiquitin carrier protein E2,Ubiquitin-protein ligase E2 |
| 4 | E (R) | DET1 homolog | polymer | 550 | 63931.4 | 1 | UniProt (Q7L5Y6) | Homo sapiens (human) | De-etiolated-1 homolog |
| 5 | F (S) | DNA damage-binding protein 1 | polymer | 1140 | 127097.5 | 1 | UniProt (Q16531) | Homo sapiens (human) | DDB p127 subunit,DNA damage-binding protein a,DDBa,Damage-specific DNA-binding protein 1,HBV X-associated protein 1,XAP-1,UV-damaged DNA-binding factor,UV-damaged DNA-binding protein 1,UV-DDB 1,XPE-binding factor,XPE-BF,Xeroderma pigmentosum group E-complementing protein,XPCe |
Sequence modifications
C: 1 - 201 (UniProt: Q96LR5)
| PDB | External Database | Details |
|---|---|---|
| Gly 76 | Ser 76 | engineered mutation |
| Ser 139 | Cys 139 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 386258.6 | |
| All* | Total formula weight | 386258.6 |
