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9LTP

Crystal structure of human RAB43 in GDP-AlF3 transition state complex with USP6NL TBC domain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
USP6 N-terminal-like proteinpolymer36744076.72UniProt (Q92738)
Pfam (PF00566)
Homo sapiens (human)Related to the N-terminus of tre,RN-tre
2B, D
(B, D)
Ras-related protein Rab-43polymer19121064.82UniProt (Q86YS6)
Pfam (PF00071)
Homo sapiens (human)Ras-related protein Rab-41
3E, K
(B, D)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
4F, L
(B, D)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.22Chemie (GDP)
5G, M
(B, D)
ALUMINUM FLUORIDEnon-polymer84.02Chemie (AF3)
6H, I, J, N
(B, C, D)
DI(HYDROXYETHYL)ETHERnon-polymer106.14Chemie (PEG)
7O, P, Q, R
(A, B, C, D)
waterwater18.0110Chemie (HOH)
Sequence modifications
A, C: 1 - 365 (UniProt: Q92738)
PDBExternal DatabaseDetails
Gly -1-expression tag
His 0-expression tag
B, D: 1 - 190 (UniProt: Q86YS6)
PDBExternal DatabaseDetails
Gly 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight130283.1
Non-Polymers*Number of molecules10
Total formula weight1527.4
All*Total formula weight131810.5
*Water molecules are not included.

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PDB entries from 2026-03-11

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