9LSL

The crystal structure of PDE5A with L1

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	cGMP-specific 3',5'-cyclic phosphodiesterase	polymer	326	37788.5	1	UniProt (O76074) Pfam (PF00233)	Homo sapiens (human)	cGMP-binding cGMP-specific phosphodiesterase,CGB-PDE
2	B (A)	(13~{S},15~{R})-15-(3-chloranyl-4-methoxy-phenyl)-12-ethanoyl-8,12,16-triazatetracyclo[7.7.1.0^{2,7}.0^{13,17}]heptadeca-1(17),2,4,6,8-pentaene-4-carbonitrile	non-polymer		432.9	1	Chemie (A1ELJ)
3	C (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
4	D (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
5	E (A)	water	water		18.0	39	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	37788.5
Non-Polymers*	Number of molecules	3
	Total formula weight	522.6
All*	Total formula weight	38311.1

*Water molecules are not included.