9LOV
LGP2:MDA5:dsRNA filament
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (Y) | RNA (45-MER) | polymer | 45 | 14278.4 | 1 | uncultured archaeon | ||
| 2 | B (X) | RNA (45-MER) | polymer | 45 | 14553.7 | 1 | uncultured archaeon | ||
| 3 | C (A) | ATP-dependent RNA helicase DHX58 | polymer | 678 | 76742.9 | 1 | UniProt (Q96C10) | Homo sapiens (human) | ATP-dependent helicase LGP2,Protein D11Lgp2 homolog,RIG-I-like receptor 3,RLR-3,RIG-I-like receptor LGP2,RLR |
| 4 | D, E (B, C) | Interferon-induced helicase C domain-containing protein 1 | polymer | 739 | 84986.8 | 2 | UniProt (Q9BYX4) | Homo sapiens (human) | Clinically amyopathic dermatomyositis autoantigen 140 kDa,CADM-140 autoantigen,Helicase with 2 CARD domains,Helicard,Interferon-induced with helicase C domain protein 1,Melanoma differentiation-associated protein 5,MDA-5,Murabutide down-regulated protein,RIG-I-like receptor 2,RLR-2,RNA helicase-DEAD box protein 116 |
| 5 | F, I, L (A, B, C) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 3 | Chemie (ADP) | |||
| 6 | G, J, M (A, B, C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 7 | H, K, N (A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) |
Sequence modifications
A: 1 - 678 (UniProt: Q96C10)
B, C: 287 - 1025 (UniProt: Q9BYX4)
| PDB | External Database | Details |
|---|---|---|
| Arg 425 | Gln 425 | variant |
| PDB | External Database | Details |
|---|---|---|
| Arg 495 | Gly 495 | variant |
| Arg 843 | His 843 | variant |
| Thr 946 | Ala 946 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 275548.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1550.7 | |
| All* | Total formula weight | 277099.3 |
