9LMZ
hAGO2-MID in complex with a chemical modified uridine monophosphate
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Protein argonaute-2 | polymer | 137 | 15266.9 | 3 | UniProt (Q9UKV8) Pfam (PF16487) | Homo sapiens (human) | Argonaute2,hAgo2,Argonaute RISC catalytic component 2,Eukaryotic translation initiation factor 2C 2,eIF-2C 2,eIF2C 2,PAZ Piwi domain protein,PPD,Protein slicer |
| 2 | D, F, G (A, B, C) | [(2R,3S,4R,5R)-5-[2,4-bis(oxidanylidene)thieno[2,3-d]pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate | non-polymer | 380.3 | 3 | Chemie (A1EY1) | |||
| 3 | E (B) | (4S)-4-amino-5-hydroxypentanamide | non-polymer | 132.2 | 1 | Chemie (ECC) | |||
| 4 | H, I, J (A, B, C) | water | water | 18.0 | 333 | Chemie (HOH) |
Sequence modifications
A, B, C: 440 - 574 (UniProt: Q9UKV8)
| PDB | External Database | Details |
|---|---|---|
| Gln 575 | - | expression tag |
| Gln 576 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 45800.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1273.0 | |
| All* | Total formula weight | 47073.8 |
