9LGU

Crystal structure of Bcl-xL in complex with stapled HRK peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, C, E, G, I...)	Bcl-2-like protein 1	polymer	218	24545.9	6	UniProt (Q07817) Pfam (PF02180) Pfam (PF00452)	Homo sapiens (human)	BCL-XL,Bcl2-L-1,Apoptosis regulator Bcl-X
2	G, H, I, J, K... (B, D, F, H, L...)	Activator of apoptosis harakiri	polymer	24	2783.3	6	UniProt (O00198)	Homo sapiens	BH3-interacting domain-containing protein 3,Neuronal death protein DP5
3	M, N, O, P, Q (A, C, I, B, D)	MAGNESIUM ION	non-polymer		24.3	5	Chemie (MG)

Sequence modifications

A, C, E, G, I, K: 1 - 209 (UniProt: Q07817)

PDB	External Database	Details
Ser 0	-	expression tag
Leu 210	-	expression tag
Glu 211	-	expression tag
His 212	-	expression tag
His 213	-	expression tag
His 214	-	expression tag
His 215	-	expression tag
His 216	-	expression tag
His 217	-	expression tag

B, D, F, H, L, M: 27 - 50 (UniProt: O00198)

PDB	External Database	Details
Leu 33	Thr 33	conflict
Mk8 35	Ala 35	conflict
Mk8 39	Ala 39	conflict

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	163975.2
Non-Polymers*	Number of molecules	5
	Total formula weight	121.5
All*	Total formula weight	164096.7

*Water molecules are not included.