9L7E
Crystal structure of human kinesin-1 motor domain (G234A mutant) in complex with ADP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Kinesin-1 heavy chain | polymer | 355 | 40016.9 | 1 | UniProt (P33176) Pfam (PF00225) | Homo sapiens (human) | Conventional kinesin heavy chain,Ubiquitous kinesin heavy chain,UKHC |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 4 | D (A) | water | water | 18.0 | 53 | Chemie (HOH) |
Sequence modifications
A: 1 - 349 (UniProt: P33176)
| PDB | External Database | Details |
|---|---|---|
| Ser 7 | Cys 7 | conflict |
| Ala 65 | Cys 65 | conflict |
| Ala 168 | Cys 168 | conflict |
| Ser 174 | Cys 174 | conflict |
| Ala 234 | Gly 234 | engineered mutation |
| Ala 294 | Cys 294 | conflict |
| Ser 330 | Cys 330 | conflict |
| His 350 | - | expression tag |
| His 351 | - | expression tag |
| His 352 | - | expression tag |
| His 353 | - | expression tag |
| His 354 | - | expression tag |
| His 355 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40016.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 451.5 | |
| All* | Total formula weight | 40468.4 |
