9L2O
Cryo-EM structure and rational engineering of a novel efficient ochratoxin A-detoxifying amidohydrolase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (B, A, C, D, E...) | Imidazolonepropionase | polymer | 408 | 43481.8 | 8 | UniProt (A0A286D6Z1) | Pseudoxanthomonas wuyuanensis | |
| 2 | AA, BA, DA, EA, I... (G, H, B, A, C...) | ZINC ION | non-polymer | 65.4 | 16 | Chemie (ZN) | |||
| 3 | CA, FA, K, N, Q... (G, H, B, A, C...) | (2~{S})-2-[[(3~{R})-5-chloranyl-3-methyl-8-oxidanyl-1-oxidanylidene-3,4-dihydroisochromen-7-yl]carbonylamino]-3-phenyl-propanoic acid | non-polymer | 403.8 | 8 | Chemie (97U) |
Sequence modifications
B, A, C, D, E, F, G, H: 21 - 428 (UniProt: A0A286D6Z1)
| PDB | External Database | Details |
|---|---|---|
| Tyr 88 | Gly 88 | engineered mutation |
| Ala 325 | Ile 325 | engineered mutation |
| Asn 344 | Asp 344 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 347854.6 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 4277.0 | |
| All* | Total formula weight | 352131.6 |
