9KWL
hCES1A contently binding with compound F-3 at the catalytic pocket.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Liver carboxylesterase 1 | polymer | 533 | 58800.4 | 1 | UniProt (P23141) Pfam (PF00135) | Homo sapiens (human) | Acyl-coenzyme A:cholesterol acyltransferase,ACAT,Brain carboxylesterase hBr1,Carboxylesterase 1,CE-1,hCE-1,Cholesteryl ester hydrolase,CEH,Cocaine carboxylesterase,Egasyn,HMSE,Methylumbelliferyl-acetate deacetylase 1,Monocyte/macrophage serine esterase,Retinyl ester hydrolase,REH,Serine esterase 1,Triacylglycerol hydrolase,TGH |
| 2 | B (A) | (1R)-1-(3,4-dichlorophenyl)-2,2,2-tris(fluoranyl)ethanol | non-polymer | 245.0 | 1 | Chemie (A1EIY) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | water | water | 18.0 | 557 | Chemie (HOH) |
Sequence modifications
A: 4 - 536 (UniProt: P23141)
| PDB | External Database | Details |
|---|---|---|
| Gln 344 | Met 361 | conflict |
| Met 345 | Gln 362 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 58800.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 269.3 | |
| All* | Total formula weight | 59069.7 |
