9KVS

Structure of SB290157 bound to human C3aR in complex with Go (Receptor Ligand Focused map)

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (C)	Muscarinic acetylcholine receptor M4,C3a anaphylatoxin chemotactic receptor	polymer	538	59808.4	1	UniProt (P08173) UniProt (Q16581)	Homo sapiens (human)	C3AR,C3a-R
2	B (C)	(2S)-5-[bis(azanyl)methylideneamino]-2-[2-(2,2-diphenylethoxy)ethanoylamino]pentanoic acid	non-polymer		412.5	1	Chemie (A1L6Y) PubChem (5311120)

Sequence modifications

C: -30 - -9 (UniProt: P08173)

PDB	External Database	Details
Met -55	-	initiating methionine
Gly -54	-	expression tag
Lys -53	-	expression tag
Thr -52	-	expression tag
Ile -51	-	expression tag
Ile -50	-	expression tag
Ala -49	-	expression tag
Leu -48	-	expression tag
Ser -47	-	expression tag
Tyr -46	-	expression tag
Ile -45	-	expression tag
Phe -44	-	expression tag
Cys -43	-	expression tag
Leu -42	-	expression tag
Val -41	-	expression tag
Phe -40	-	expression tag
Ala -39	-	expression tag
Asp -38	-	expression tag
Tyr -37	-	expression tag
Lys -36	-	expression tag
Asp -35	-	expression tag
Asp -34	-	expression tag
Asp -33	-	expression tag
Asp -32	-	expression tag
Ala -31	-	expression tag
Leu -8	-	linker
Glu -7	-	linker
Val -6	-	linker
Leu -5	-	linker
Phe -4	-	linker
Gln -3	-	linker
Gly -2	-	linker
Pro -1	-	linker
Gly 0	-	linker
Ser 1	-	linker

C: 2 - 482 (UniProt: Q16581)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	59808.4
Non-Polymers*	Number of molecules	1
	Total formula weight	412.5
All*	Total formula weight	60220.9

*Water molecules are not included.