9KVS
Structure of SB290157 bound to human C3aR in complex with Go (Receptor Ligand Focused map)
This is a non-PDB format compatible entry.
Functional Information from PROSITE/UniProt
| site_id | PS00237 |
| Number of Residues | 17 |
| Details | G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. ASVfLLTAISLDRCLvV |
| Chain | Residue | Details |
| C | ALA108-VAL124 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 21 |
| Details | Transmembrane: {"description":"Helical; Name=3","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 19 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 22 |
| Details | Transmembrane: {"description":"Helical; Name=4","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=6","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 19 |
| Details | Transmembrane: {"description":"Helical; Name=7","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 25 |
| Details | Transmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"37852260","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8HK2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8HK3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I95","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I97","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I9L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I9S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8J6D","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 55 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"37852260","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8HK2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8HK3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I95","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I97","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I9L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I9S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8J6D","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 24 |
| Details | Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"37852260","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8HK2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8HK3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I95","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I97","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I9L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I9S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8J6D","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 13 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"37852260","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8HK2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8HK3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I95","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I97","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I9L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I9S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8J6D","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 26 |
| Details | Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"37852260","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8HK2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8HK3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I95","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I97","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I9L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I9S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8J6D","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 19 |
| Details | Transmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"37852260","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8HK2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8HK3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I95","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I97","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I9L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I9S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8J6D","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 21 |
| Details | Transmembrane: {"description":"Helical; Name=5","evidences":[{"source":"PubMed","id":"37852260","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8HK2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8HK3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I95","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I97","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I9L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I9S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8J6D","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 25 |
| Details | Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"37852260","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8HK2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8HK3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I95","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I97","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I9L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I9S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8J6D","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 23 |
| Details | Transmembrane: {"description":"Helical; Name=7","evidences":[{"source":"PubMed","id":"37852260","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8HK2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8HK3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I95","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I97","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I9L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8I9S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8J6D","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Sulfotyrosine","evidences":[{"source":"PubMed","id":"12871936","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
