9KVO

Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation D132E

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	KCNQ1 helixAB	polymer	66	7937.3	2		Homo sapiens
2	C, D (C, D)	Calmodulin-1	polymer	149	16866.6	2	UniProt (P0DP23) Pfam (PF13499)	Homo sapiens (human)
3	E, F, G, H (C, D)	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)

Sequence modifications

C, D: 1 - 149 (UniProt: P0DP23)

PDB	External Database	Details
Glu 132	Asp 132	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	49607.7
Non-Polymers*	Number of molecules	4
	Total formula weight	160.3
All*	Total formula weight	49768.0

*Water molecules are not included.