9KUW

Cryo-EM structure of dimeric APJR and two Beta-arrestins complex with small molecules

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Beta arrestion-scFv30	polymer	621	68345.0	2		Homo sapiens
2	C, D (Q, R)	Apelin receptor	polymer	506	57685.5	2	Pfam (PF00001) UniProt (by SIFTS) (P35414)	Homo sapiens
3	E, H (Q, R)	(1~{S},2~{S})-~{N}-[4-(2,6-dimethoxyphenyl)-5-(6-methylpyridin-2-yl)-1,2,4-triazol-3-yl]-1-(5-methylpyrimidin-2-yl)-1-oxidanyl-propane-2-sulfonamide	non-polymer		525.6	2	Chemie (A1L6R)
4	F, G (Q, R)	CHOLESTEROL	non-polymer		386.7	2	Chemie (CLR)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	252061.1
Non-Polymers*	Number of molecules	4
	Total formula weight	1824.5
All*	Total formula weight	253885.5

*Water molecules are not included.