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9KUU

Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation D130G

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, D)
KCNQ1 helixABpolymer667937.32Homo sapiens
2B, D
(C, E)
Calmodulin-1polymer14916794.52UniProt (P0DP23)
Pfam (PF13499)
Homo sapiens (human)
3E, F, G, H
(C, E)
CALCIUM IONnon-polymer40.14Chemie (CA)
4I, J, K, L
(A, C, D, E)
waterwater18.059Chemie (HOH)
Sequence modifications
C, E: 1 - 149 (UniProt: P0DP23)
PDBExternal DatabaseDetails
Gly 130Asp 130engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight49463.5
Non-Polymers*Number of molecules4
Total formula weight160.3
All*Total formula weight49623.9
*Water molecules are not included.

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PDB entries from 2026-02-04

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