Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (I) | Histone-lysine N-methyltransferase EZH2 | polymer | 754 | 86597.5 | 1 | UniProt (Q15910) | Homo sapiens (human) | ENX-1,Enhancer of zeste homolog 2,Lysine N-methyltransferase 6 |
| 2 | B, D (C, E) | H3K27me3 | polymer | 10 | 1045.3 | 2 | Homo sapiens | ||
| 3 | C (D) | Polycomb protein EED | polymer | 362 | 41808.5 | 1 | UniProt (O75530) | Homo sapiens (human) | hEED,Embryonic ectoderm development protein,WD protein associating with integrin cytoplasmic tails 1,WAIT-1 |
| 4 | E (O) | Polycomb protein SUZ12 | polymer | 597 | 69661.2 | 1 | UniProt (Q15022) | Homo sapiens (human) | Chromatin precipitated E2F target 9 protein,ChET 9 protein,Joined to JAZF1 protein,Suppressor of zeste 12 protein homolog |
| 5 | F (F) | Zinc finger protein AEBP2 | polymer | 106 | 12236.2 | 1 | UniProt (Q6ZN18) | Homo sapiens (human) | Adipocyte enhancer-binding protein 2,AE-binding protein 2 |
| 6 | G (K) | RB binding protein 4, chromatin remodeling factor,Histone-binding protein RBBP4 | polymer | 492 | 55730.8 | 1 | UniProt (E9PNS6) UniProt (Q09028) | Homo sapiens (human) | Chromatin assembly factor 1 subunit C,CAF-1 subunit C,Chromatin assembly factor I p48 subunit,CAF-I 48 kDa subunit,CAF-I p48,Nucleosome-remodeling factor subunit RBAP48,Retinoblastoma-binding protein 4,RBBP-4,Retinoblastoma-binding protein p48 |
| 7 | H (I) | 2-[2-[[4-[(8-chloranyl-1,7-naphthyridin-2-yl)amino]cyclohexyl]methylamino]pyrimidin-5-yl]-N-(oxetan-3-yl)ethanamide | non-polymer | 482.0 | 1 | Chemie (A1EGC) | |||
| 8 | I (I) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) PubChem (439155) |
Sequence modifications
I: 1 - 746 (UniProt: Q15910)
K: -81 - 3 (UniProt: E9PNS6)
K: 4 - 495 (UniProt: Q09028)
| PDB | External Database | Details |
|---|---|---|
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
K: 4 - 495 (UniProt: Q09028)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 268124.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 866.4 | |
| All* | Total formula weight | 268991.1 |






