Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

9KNH

Structural complex of FTO bound with Dac590

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Alpha-ketoglutarate-dependent dioxygenase FTOpolymer47854934.01UniProt (Q9C0B1)
Pfam (PF12933)
Pfam (PF12934)
Homo sapiens (human)Fat mass and obesity-associated protein,U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO,U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO,mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO,m6A(m)-demethylase FTO,mRNA N(6)-methyladenosine demethylase FTO,tRNA N1-methyl adenine demethylase FTO
2B
(A)
2-[[2-chloranyl-4-(3,5-dimethyl-1,2-oxazol-4-yl)-6-fluoranyl-phenyl]amino]-5-methoxy-benzoic acidnon-polymer390.81Chemie (A1EF4)
3C
(A)
N-OXALYLGLYCINEnon-polymer147.11Chemie (OGA)
4D
(A)
FE (III) IONnon-polymer55.81Chemie (FE)
Sequence modifications
A: 32 - 505 (UniProt: Q9C0B1)
PDBExternal DatabaseDetails
Gly 28-expression tag
Ser 29-expression tag
His 30-expression tag
Met 31-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight54934.0
Non-Polymers*Number of molecules3
Total formula weight593.7
All*Total formula weight55527.7
*Water molecules are not included.

243531

PDB entries from 2025-10-22

PDB statisticsPDBj update infoContact PDBjnumon