9KHI
Cryo-EM structure of heteromeric TRPC channel
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Short transient receptor potential channel 1 | polymer | 797 | 91688.2 | 1 | UniProt (P48995) Pfam (PF08344) Pfam (PF00520) | Homo sapiens (human) | TrpC1,Transient receptor protein 1,TRP-1 |
| 2 | B, C, D (D, C, B) | Short transient receptor potential channel 5 | polymer | 773 | 89951.9 | 3 | UniProt (Q9UL62) Pfam (PF12796) Pfam (PF00023) Pfam (PF08344) Pfam (PF00520) | Homo sapiens (human) | TrpC5,Transient receptor protein 5,TRP-5,hTRP-5,hTRP5 |
| 3 | E, I, M (D, C, B) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 4 | F, J, N (D, C, B) | (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate | non-polymer | 594.9 | 3 | Chemie (YZY) | |||
| 5 | G, K, O (D, C, B) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 3 | Chemie (Y01) | |||
| 6 | H, L, P (D, C, B) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) |
Sequence modifications
A: 1 - 793 (UniProt: P48995)
D, C, B: 1 - 765 (UniProt: Q9UL62)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Val -1 | - | expression tag |
| Asp 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 766 | - | expression tag |
| Arg 767 | - | expression tag |
| Leu 768 | - | expression tag |
| Glu 769 | - | expression tag |
| Val 770 | - | expression tag |
| Leu 771 | - | expression tag |
| Phe 772 | - | expression tag |
| Gln 773 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 361543.8 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 3561.5 | |
| All* | Total formula weight | 365105.3 |
