9KGL
Structure of KATP channel in complex with centipede toxin SpTx1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | ATP-sensitive inward rectifier potassium channel 11 | polymer | 390 | 43595.7 | 4 | UniProt (Q14654) Pfam (PF01007) Pfam (PF17655) | Homo sapiens (human) | IKATP,Inward rectifier K(+) channel Kir6.2,Potassium channel,inwardly rectifying subfamily J member 11 |
| 2 | B, D, F, H (B, D, F, H) | ATP-binding cassette sub-family C member 8 isoform X2 | polymer | 1582 | 177295.6 | 4 | UniProt (A0A1U7R319) Pfam (PF00664) Pfam (PF00005) | Mesocricetus auratus (golden hamster) | |
| 3 | I (I) | SpTx1 | polymer | 56 | 6527.6 | 1 | Scolopendra polymorpha | ||
| 4 | J, L, M, O, P... (A, B, C, D, E...) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 8 | Chemie (ATP) | |||
| 5 | K, N, Q, T (B, D, F, H) | 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide | non-polymer | 494.0 | 4 | Chemie (GBM) |
Sequence modifications
A, C, E, G: 1 - 390 (UniProt: Q14654)
B, D, F, H: 1 - 1582 (UniProt: A0A1U7R319)
| PDB | External Database | Details |
|---|---|---|
| Glu 23 | Lys 23 | variant |
| Glu 52 | Gln 52 | conflict |
| Ile 337 | Val 337 | variant |
| PDB | External Database | Details |
|---|---|---|
| Lys 203 | Glu 203 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 890092.8 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 6033.5 | |
| All* | Total formula weight | 896126.3 |
