9KDG
CryoEM structure of Calcineurin-fusion Human endothelin receptor type-B in the ligand-free form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Calcineurin-fusion endothelin receptor type-B | polymer | 908 | 102498.9 | 1 | Homo sapiens | ||
| 2 | B (F) | Peptidyl-prolyl cis-trans isomerase FKBP1B | polymer | 116 | 12771.5 | 1 | UniProt (P68106) Pfam (PF00254) | Homo sapiens (human) | PPIase FKBP1B,12.6 kDa FK506-binding protein,12.6 kDa FKBP,FKBP-12.6,FK506-binding protein 1B,FKBP-1B,Immunophilin FKBP12.6,Rotamase,h-FKBP-12 |
| 3 | C, D, E, F (A) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 4 | G (A) | FE (III) ION | non-polymer | 55.8 | 1 | Chemie (FE) | |||
| 5 | H (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 6 | I (F) | 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN | non-polymer | 804.0 | 1 | Chemie (FK5) |
Sequence modifications
F: 4 - 110 (UniProt: P68106)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Gly 2 | - | expression tag |
| Ser 3 | - | expression tag |
| His 111 | - | expression tag |
| His 112 | - | expression tag |
| His 113 | - | expression tag |
| His 114 | - | expression tag |
| His 115 | - | expression tag |
| His 116 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 115270.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1085.6 | |
| All* | Total formula weight | 116356.0 |
