9K9L
Cryo-EM structure of the human CENP-A-H4 octasome.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | Histone H3-like centromeric protein A | polymer | 143 | 16305.9 | 4 | UniProt (P49450) Pfam (PF00125) | Homo sapiens (human) | Centromere autoantigen A,Centromere protein A,CENP-A |
| 2 | B, D, F, H (B, D, F, H) | Histone H4 | polymer | 106 | 11676.7 | 4 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (human) | |
| 3 | I (I) | Widom601 DNA FW (145-MER) | polymer | 145 | 44520.4 | 1 | synthetic construct | ||
| 4 | J (J) | Widom601 DNA RV (145-MER) | polymer | 145 | 44991.7 | 1 | synthetic construct |
Sequence modifications
A, C, E, G: 1 - 140 (UniProt: P49450)
B, D, F, H: 0 - 102 (UniProt: P62805)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 201442.5 | |
| All* | Total formula weight | 201442.5 |
